Insulin R/CD220 Protein 1544-IR-050/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemInsulin R/CD220 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number1544-IR-050/CF
SpeciesHuman
Quantity50 ug
FormatLyophilized from a 0.2 µm filtered solution in PBS
Molecule NameInsulin R/CD220
NCBI Full Gene Nameinsulin receptor
NCBI Gene AliasesCD220, HHF5
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 122-135 kDa and 33-43 kDa, reducing conditions
Theoretical: 82.9 kDa ( alpha subunit), 22.9 kDa ( beta subunit)
Brand/TrademarkR&D Systems, a Bio-Techne Brand
ApplicationsBinding Activity
Conjugate/TagUnconjugated
Source/Expression SystemNS0-derived Recombinant Human Insulin R/CD220 (aa 28-944) Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Available conjugates: Unconjugated

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(1) An aptamer agonist of the insulin receptor acts as a positive or negative allosteric modulator, depending on its concentrationExperimental & molecular medicineApril 1, 2022Yunn NO, Lee J, Lee HS, Oh EJ, Park M, Park S, Jin SY, Shin E, Lee JWY, Kim Y, et al.

(4) Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysisNatureApril 5, 2018Scapin G, Dandey VP, Zhang Z, Prosise W, Hruza A, Kelly T, Mayhood T, Strickland C, Potter CS, Carragher B.

(5) A Small Insulinomimetic Molecule Also Improves Insulin Sensitivity in Diabetic MicePloS oneJanuary 1, 2017Mukherjee S, Chattopadhyay M, Bhattacharya S, Dasgupta S, Hussain S, Bharadwaj SK, Talukdar D, Usmani A, Pradhan BS, Majumdar SS, et al.

Insulin R/CD220 Protein from R&D Systems, a Bio-Techne Brand